.select2-container{box-sizing:border-box;display:inline-block;margin:0;position:relative;vertical-align:middle}.select2-container .select2-selection--single{box-sizing:border-box;cursor:pointer;display:block;height:28px;user-select:none;-webkit-user-select:none}.select2-container .select2-selection--single .select2-selection__rendered{display:block;padding-left:8px;padding-right:20px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.select2-container .select2-selection--single .select2-selection__clear{position:relative}.select2-container[dir=rtl] .select2-selection--single .select2-selection__rendered{padding-right:8px;padding-left:20px}.select2-container .select2-selection--multiple{box-sizing:border-box;cursor:pointer;display:block;min-height:32px;user-select:none;-webkit-user-select:none}.select2-container .select2-selection--multiple .select2-selection__rendered{display:inline-block;overflow:hidden;padding-left:8px;text-overflow:ellipsis;white-space:nowrap}.select2-container .select2-search--inline{float:left}.select2-container .select2-search--inline .select2-search__field{box-sizing:border-box;border:none;font-size:100%;margin-top:5px;padding:0}.select2-container .select2-search--inline .select2-search__field::-webkit-search-cancel-button{-webkit-appearance:none}.select2-dropdown{background-color:#fff;border:1px solid #aaa;border-radius:3px;box-sizing:border-box;display:block;position:absolute;left:-100000px;width:100%;z-index:1051}.select2-results{display:block}.select2-results__options{list-style:none;margin:0;padding:0}.select2-results__option{padding:6px;user-select:none;-webkit-user-select:none}.select2-results__option[aria-selected]{cursor:pointer}.select2-container--open .select2-dropdown{left:0}.select2-container--open .select2-dropdown--above{border-bottom:none;border-bottom-left-radius:0;border-bottom-right-radius:0}.select2-container--open .select2-dropdown--below{border-top:none;border-top-left-radius:0;border-top-right-radius:0}.select2-search--dropdown{display:block;padding:4px}.select2-search--dropdown .select2-search__field{padding:4px;width:100%;box-sizing:border-box}.select2-search--dropdown .select2-search__field::-webkit-search-cancel-button{-webkit-appearance:none}.select2-search--dropdown.select2-search--hide{display:none}.select2-close-mask{border:0;margin:0;padding:0;display:block;position:fixed;left:0;top:0;min-height:100%;min-width:100%;height:auto;width:auto;opacity:0;z-index:99;background-color:#fff;filter:alpha(opacity=0)}.select2-hidden-accessible{border:0!important;clip:rect(0 0 0 0)!important;height:1px!important;margin:-1px!important;overflow:hidden!important;padding:0!important;position:absolute!important;width:1px!important}.select2-container--classic .select2-results>.select2-results__options,.select2-container--default .select2-results>.select2-results__options{max-height:200px;overflow-y:auto}.select2-container--default .select2-selection--single{background-color:#fff;border:1px solid #aaa;border-radius:3px}.select2-container--default .select2-selection--single .select2-selection__rendered{color:#444;line-height:28px}.select2-container--default .select2-selection--single .select2-selection__clear{cursor:pointer;float:right;font-weight:700}.select2-container--default .select2-selection--single .select2-selection__arrow{height:26px;position:absolute;top:1px;right:1px;width:20px}.select2-container--default .select2-selection--single .select2-selection__arrow b{border-color:#888 transparent transparent;border-style:solid;border-width:5px 4px 0;height:0;left:50%;margin-left:-4px;margin-top:-2px;position:absolute;top:50%;width:0}.select2-container--default[dir=rtl] .select2-selection--single 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.select2-selection--multiple .select2-selection__placeholder{color:#999;margin-top:5px;float:left}.select2-container--default .select2-selection--multiple .select2-selection__clear{cursor:pointer;float:right;font-weight:700;margin-top:5px;margin-right:10px}.select2-container--default .select2-selection--multiple .select2-selection__choice{background-color:#e4e4e4;border:1px solid #aaa;border-radius:4px;cursor:default;float:left;margin-right:5px;margin-top:5px;padding:0 5px}.select2-container--default .select2-selection--multiple .select2-selection__choice__remove{color:#999;cursor:pointer;display:inline-block;font-weight:700;margin-right:2px}.select2-container--default .select2-selection--multiple .select2-selection__choice__remove:hover{color:#333}.select2-container--default[dir=rtl] .select2-selection--multiple .select2-search--inline,.select2-container--default[dir=rtl] .select2-selection--multiple .select2-selection__choice,.select2-container--default[dir=rtl] .select2-selection--multiple .select2-selection__placeholder{float:right}.select2-container--default[dir=rtl] .select2-selection--multiple .select2-selection__choice{margin-left:5px;margin-right:auto}.select2-container--default[dir=rtl] .select2-selection--multiple .select2-selection__choice__remove{margin-left:2px;margin-right:auto}.select2-container--default.select2-container--focus .select2-selection--multiple{border:1px solid #000;outline:0}.select2-container--default.select2-container--disabled .select2-selection--multiple{background-color:#eee;cursor:default}.select2-container--default.select2-container--disabled .select2-selection__choice__remove{display:none}.select2-container--default.select2-container--open.select2-container--above .select2-selection--multiple,.select2-container--default.select2-container--open.select2-container--above 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.select2-results__option .select2-results__option .select2-results__group{padding-left:0}.select2-container--default .select2-results__option .select2-results__option .select2-results__option{margin-left:-1em;padding-left:2em}.select2-container--default .select2-results__option .select2-results__option .select2-results__option .select2-results__option{margin-left:-2em;padding-left:3em}.select2-container--default .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option{margin-left:-3em;padding-left:4em}.select2-container--default .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option{margin-left:-4em;padding-left:5em}.select2-container--default .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option .select2-results__option{margin-left:-5em;padding-left:6em}.select2-container--default .select2-results__option--highlighted[aria-selected]{background-color:#5897fb;color:#fff}.select2-container--default .select2-results__group{cursor:default;display:block;padding:6px}.select2-container--classic .select2-selection--single{background-color:#f7f7f7;border:1px solid #aaa;border-radius:3px;outline:0;background-image:-webkit-linear-gradient(top,#fff 50%,#eee 100%);background-image:-o-linear-gradient(top,#fff 50%,#eee 100%);background-image:linear-gradient(to bottom,#fff 50%,#eee 100%);background-repeat:repeat-x;filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#FFFFFFFF', endColorstr='#FFEEEEEE', GradientType=0)}.select2-container--classic .select2-selection--single:focus{border:1px solid #5897fb}.select2-container--classic .select2-selection--single .select2-selection__rendered{color:#444;line-height:28px}.select2-container--classic .select2-selection--single .select2-selection__clear{cursor:pointer;float:right;font-weight:700;margin-right:10px}.select2-container--classic .select2-selection--single .select2-selection__placeholder{color:#999}.select2-container--classic .select2-selection--single .select2-selection__arrow{background-color:#ddd;border:none;border-left:1px solid #aaa;border-top-right-radius:4px;border-bottom-right-radius:4px;height:26px;position:absolute;top:1px;right:1px;width:20px;background-image:-webkit-linear-gradient(top,#eee 50%,#ccc 100%);background-image:-o-linear-gradient(top,#eee 50%,#ccc 100%);background-image:linear-gradient(to bottom,#eee 50%,#ccc 100%);background-repeat:repeat-x;filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#FFEEEEEE', endColorstr='#FFCCCCCC', GradientType=0)}.select2-container--classic .select2-selection--single .select2-selection__arrow b{border-color:#888 transparent transparent;border-style:solid;border-width:5px 4px 0;height:0;left:50%;margin-left:-4px;margin-top:-2px;position:absolute;top:50%;width:0}.select2-container--classic[dir=rtl] .select2-selection--single .select2-selection__clear{float:left}.select2-container--classic[dir=rtl] .select2-selection--single .select2-selection__arrow{border:none;border-right:1px solid #aaa;border-radius:4px 0 0 4px;left:1px;right:auto}.select2-container--classic.select2-container--open .select2-selection--single{border:1px solid #5897fb}.select2-container--classic.select2-container--open .select2-selection--single .select2-selection__arrow{background:0 0;border:none}.select2-container--classic.select2-container--open .select2-selection--single .select2-selection__arrow b{border-color:transparent transparent #888;border-width:0 4px 5px}.select2-container--classic.select2-container--open.select2-container--above .select2-selection--single{border-top:none;border-top-left-radius:0;border-top-right-radius:0;background-image:-webkit-linear-gradient(top,#fff 0,#eee 50%);background-image:-o-linear-gradient(top,#fff 0,#eee 50%);background-image:linear-gradient(to bottom,#fff 0,#eee 50%);background-repeat:repeat-x;filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#FFFFFFFF', endColorstr='#FFEEEEEE', GradientType=0)}.select2-container--classic.select2-container--open.select2-container--below .select2-selection--single{border-bottom:none;border-bottom-left-radius:0;border-bottom-right-radius:0;background-image:-webkit-linear-gradient(top,#eee 50%,#fff 100%);background-image:-o-linear-gradient(top,#eee 50%,#fff 100%);background-image:linear-gradient(to bottom,#eee 50%,#fff 100%);background-repeat:repeat-x;filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#FFEEEEEE', endColorstr='#FFFFFFFF', GradientType=0)}.select2-container--classic .select2-selection--multiple{background-color:#fff;border:1px solid #aaa;border-radius:3px;cursor:text;outline:0}.select2-container--classic .select2-selection--multiple:focus{border:1px solid #5897fb}.select2-container--classic .select2-selection--multiple .select2-selection__rendered{list-style:none;margin:0;padding:0 5px}.select2-container--classic .select2-selection--multiple .select2-selection__clear{display:none}.select2-container--classic .select2-selection--multiple .select2-selection__choice{background-color:#e4e4e4;border:1px solid #aaa;border-radius:4px;cursor:default;float:left;margin-right:5px;margin-top:5px;padding:0 5px}.select2-container--classic .select2-selection--multiple .select2-selection__choice__remove{color:#888;cursor:pointer;display:inline-block;font-weight:700;margin-right:2px}.select2-container--classic .select2-selection--multiple .select2-selection__choice__remove:hover{color:#555}.select2-container--classic[dir=rtl] .select2-selection--multiple .select2-selection__choice{float:right;margin-left:5px;margin-right:auto}.select2-container--classic[dir=rtl] .select2-selection--multiple .select2-selection__choice__remove{margin-left:2px;margin-right:auto}.select2-container--classic.select2-container--open .select2-selection--multiple{border:1px solid #5897fb}.select2-container--classic.select2-container--open.select2-container--above .select2-selection--multiple{border-top:none;border-top-left-radius:0;border-top-right-radius:0}.select2-container--classic.select2-container--open.select2-container--below .select2-selection--multiple{border-bottom:none;border-bottom-left-radius:0;border-bottom-right-radius:0}.select2-container--classic .select2-search--dropdown .select2-search__field{border:1px solid #aaa;outline:0}.select2-container--classic .select2-search--inline .select2-search__field{outline:0;box-shadow:none}.select2-container--classic .select2-dropdown{background-color:#fff;border:1px solid transparent}.select2-container--classic .select2-dropdown--above{border-bottom:none}.select2-container--classic .select2-dropdown--below{border-top:none}.select2-container--classic .select2-results__option[role=group]{padding:0}.select2-container--classic .select2-results__option[aria-disabled=true]{color:grey}.select2-container--classic .select2-results__option--highlighted[aria-selected]{background-color:#3875d7;color:#fff}.select2-container--classic .select2-results__group{cursor:default;display:block;padding:6px}.select2-container--classic.select2-container--open .select2-dropdown{border-color:#5897fb}/*! elementor - v3.29.0 - 04-06-2025 */
"use strict";
(self["webpackChunkelementorFrontend"] = self["webpackChunkelementorFrontend"] || []).push([["section-editor-handlers"],{
/***/ "../assets/dev/js/frontend/handlers/section/shapes.js":
/*!************************************************************!*\
!*** ../assets/dev/js/frontend/handlers/section/shapes.js ***!
\************************************************************/
/***/ ((__unused_webpack_module, exports, __webpack_require__) => {
Object.defineProperty(exports, "__esModule", ({
value: true
}));
exports["default"] = void 0;
__webpack_require__(/*! core-js/modules/esnext.iterator.constructor.js */ "../node_modules/core-js/modules/esnext.iterator.constructor.js");
__webpack_require__(/*! core-js/modules/esnext.iterator.find.js */ "../node_modules/core-js/modules/esnext.iterator.find.js");
class Shapes extends elementorModules.frontend.handlers.Base {
getDefaultSettings() {
return {
selectors: {
container: '> .elementor-shape-%s'
},
svgURL: elementorFrontend.config.urls.assets + 'shapes/'
};
}
getDefaultElements() {
const elements = {},
selectors = this.getSettings('selectors');
elements.$topContainer = this.$element.find(selectors.container.replace('%s', 'top'));
elements.$bottomContainer = this.$element.find(selectors.container.replace('%s', 'bottom'));
return elements;
}
isActive() {
return elementorFrontend.isEditMode();
}
getSvgURL(shapeType, fileName) {
let svgURL = this.getSettings('svgURL') + fileName + '.svg';
if (elementor.config.additional_shapes && shapeType in elementor.config.additional_shapes) {
svgURL = elementor.config.additional_shapes[shapeType];
if (-1 < fileName.indexOf('-negative')) {
svgURL = svgURL.replace('.svg', '-negative.svg');
}
}
return svgURL;
}
buildSVG(side) {
const baseSettingKey = 'shape_divider_' + side,
shapeType = this.getElementSettings(baseSettingKey),
$svgContainer = this.elements['$' + side + 'Container'];
$svgContainer.attr('data-shape', shapeType);
if (!shapeType) {
$svgContainer.empty(); // Shape-divider set to 'none'
return;
}
let fileName = shapeType;
if (this.getElementSettings(baseSettingKey + '_negative')) {
fileName += '-negative';
}
const svgURL = this.getSvgURL(shapeType, fileName);
jQuery.get(svgURL, data => {
$svgContainer.empty().append(data.childNodes[0]);
});
this.setNegative(side);
}
setNegative(side) {
this.elements['$' + side + 'Container'].attr('data-negative', !!this.getElementSettings('shape_divider_' + side + '_negative'));
}
onInit() {
if (!this.isActive(this.getSettings())) {
return;
}
super.onInit(...arguments);
['top', 'bottom'].forEach(side => {
if (this.getElementSettings('shape_divider_' + side)) {
this.buildSVG(side);
}
});
}
onElementChange(propertyName) {
const shapeChange = propertyName.match(/^shape_divider_(top|bottom)$/);
if (shapeChange) {
this.buildSVG(shapeChange[1]);
return;
}
const negativeChange = propertyName.match(/^shape_divider_(top|bottom)_negative$/);
if (negativeChange) {
this.buildSVG(negativeChange[1]);
this.setNegative(negativeChange[1]);
}
}
}
exports["default"] = Shapes;
/***/ })
}]);
//# sourceMappingURL=section-editor-handlers.46a034cbaaa10c6afa92.bundle.js.mapimport Component from './data/component';
import { Templates } from './data/commands';
export default class Module extends elementorModules.editor.utils.Module {
onElementorInit() {
const config = elementor.documents.getCurrent().config;
if ( config.support_site_editor ) {
$e.components.register( new Component() );
$e.data.deleteCache( $e.components.get( Component.namespace ), Templates.signature );
}
}
}
@keyframes wobble {
from,
to {
transform: none;
}
15% {
transform: translate3d(-25%, 0, 0) rotate3d(0, 0, 1, -5deg);
}
30% {
transform: translate3d(20%, 0, 0) rotate3d(0, 0, 1, 3deg);
}
45% {
transform: translate3d(-15%, 0, 0) rotate3d(0, 0, 1, -3deg);
}
60% {
transform: translate3d(10%, 0, 0) rotate3d(0, 0, 1, 2deg);
}
75% {
transform: translate3d(-5%, 0, 0) rotate3d(0, 0, 1, -1deg);
}
}
.wobble {
animation-name: wobble;
}
:root{--wp-admin-theme-color:#007cba;--wp-admin-theme-color--rgb:0,124,186;--wp-admin-theme-color-darker-10:#006ba1;--wp-admin-theme-color-darker-10--rgb:0,107,161;--wp-admin-theme-color-darker-20:#005a87;--wp-admin-theme-color-darker-20--rgb:0,90,135;--wp-admin-border-width-focus:2px;--wp-block-synced-color:#7a00df;--wp-block-synced-color--rgb:122,0,223;--wp-bound-block-color:var(--wp-block-synced-color)}@media(min-resolution:192dpi){:root{--wp-admin-border-width-focus:1.5px}}.wp-block-woocommerce-product-custom-fields-toggle-field__content{display:flex;gap:8px;align-items:center}.wp-block-woocommerce-product-custom-fields-toggle-field__content .components-spinner{margin:0}.wp-block-woocommerce-product-custom-fields-toggle-field__inner-blocks{margin-top:48px}{
"name": "woocommerce/filter-wrapper",
"version": "1.0.0",
"title": "Filter Block",
"category": "woocommerce",
"keywords": [ "WooCommerce" ],
"attributes": {
"filterType": {
"type": "string"
},
"heading": {
"type": "string"
}
},
"textdomain": "woocommerce",
"apiVersion": 2,
"$schema": "https://schemas.wp.org/trunk/block.json"
}
.wc-block-filter-title-placeholder{background-color:currentColor!important;border:0!important;border-radius:.25rem;border-radius:1.625em;box-shadow:none;color:currentColor!important;display:block;line-height:1;margin-bottom:12px;margin-top:12px;max-width:100%!important;max-width:max-content!important;min-width:80px;opacity:.15;outline:0!important;overflow:hidden!important;pointer-events:none;position:relative!important;width:100%;z-index:1}.wc-block-filter-title-placeholder>*{visibility:hidden}.wc-block-filter-title-placeholder:after{animation:loading__animation 1.5s ease-in-out infinite;background-image:linear-gradient(-90deg,currentColor,hsla(0,0%,96%,.302),currentColor);background-repeat:no-repeat;content:" ";display:block;height:100%;right:0;position:absolute;left:0;top:0;transform:translateX(100%)}@keyframes loading__animation{to{transform:translateX(-100%)}}@media screen and (prefers-reduced-motion:reduce){.wc-block-filter-title-placeholder{animation:none}}.wc-block-filter-title-placeholder .wc-block-active-filters__title,.wc-block-filter-title-placeholder .wc-block-attribute-filter__title,.wc-block-filter-title-placeholder .wc-block-price-filter__title,.wc-block-filter-title-placeholder .wc-block-rating-filter__title,.wc-block-filter-title-placeholder .wc-block-stock-filter__title{height:1em;margin:0}
.wp-block-woocommerce-active-filters h1,.wp-block-woocommerce-active-filters h2,.wp-block-woocommerce-active-filters h3,.wp-block-woocommerce-active-filters h4,.wp-block-woocommerce-active-filters h5,.wp-block-woocommerce-active-filters h6{text-transform:inherit}.wp-block-woocommerce-active-filters .wc-block-filter-title-placeholder .wc-block-active-filters__title{height:1em}.wc-block-active-filters{overflow:hidden}.wc-block-active-filters .wc-block-active-filters__clear-all{background:transparent;border:none;border-radius:0;box-shadow:none;color:inherit;cursor:pointer;display:inline;float:left;font-family:inherit;font-size:inherit;font-size:.875em;font-style:inherit;font-weight:inherit;font-weight:400;letter-spacing:inherit;line-height:inherit;margin:15px 0 0;padding:0;text-decoration:inherit;text-decoration:underline;text-shadow:none;text-transform:inherit;vertical-align:baseline}.wc-block-active-filters .wc-block-active-filters__clear-all:active,.wc-block-active-filters .wc-block-active-filters__clear-all:focus,.wc-block-active-filters .wc-block-active-filters__clear-all:hover{background:transparent}.wc-block-active-filters .wc-block-active-filters__clear-all:hover{color:inherit;cursor:pointer;text-decoration:none}.wc-block-active-filters .wc-block-active-filters__clear-all,.wc-block-active-filters .wc-block-active-filters__clear-all:active,.wc-block-active-filters .wc-block-active-filters__clear-all:focus,.wc-block-active-filters .wc-block-active-filters__clear-all:hover{background:transparent;color:inherit}.wc-block-active-filters 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Wirkung von Metformin Hydrochlorid – Quiminova
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Metformin Hydrochlorid ist ein bekanntes Medikament, das häufig zur Behandlung von Typ-2-Diabetes eingesetzt wird. Es gehört zur Klasse der Biguanide und hat sich als wirksam erwiesen, um den Blutzuckerspiegel zu senken und die Insulinsensitivität zu erhöhen.
https://www.invecs.ph/wirkung-von-metformin-hydrochlorid-im-detail/
Inhaltsverzeichnis
Wie Metformin wirkt
Wirkungsmechanismen von Metformin
Nebenwirkungen und Risiken
Anwendungsgebiete
1. Wie Metformin wirkt
Metformin wirkt primär durch die Senkung der hepatischen Glukoseproduktion und die Verbesserung der Insulinsensitivität. Die chemische Struktur von Metformin ermöglicht es, die Produktion von Glukose in der Leber zu dämpfen und die Glukoseverwertung in den Muskelzellen zu fördern.
2. Wirkungsmechanismen von Metformin
Die Wirkung von Metformin kann in mehrere Mechanismen unterteilt werden:
Hemmung der Glukoseproduktion: Metformin reduziert die Glukoneogenese in der Leber und verringert damit die Menge an Glukose, die ins Blut gelangt.
Erhöhung der Glukoseaufnahme: Es verbessert die Fähigkeit der Muskelzellen, Glukose aus dem Blut aufzunehmen.
Wirkung auf das Mikrobiom: Metformin kann auch das Darmmikrobiom beeinflussen, was zu einer verbesserten Glukosetoleranz führen kann.
3. Nebenwirkungen und Risiken
Obwohl Metformin im Allgemeinen gut verträglich ist, können einige Nebenwirkungen auftreten. Zu den häufigsten gehören:
Magen-Darm-Beschwerden wie Übelkeit, Durchfall und Bauchschmerzen.
Selten kann es zu einer Laktatazidose kommen, einer ernsten, aber seltenen Komplikation.
4. Anwendungsgebiete
Metformin wird nicht nur zur Behandlung von Typ-2-Diabetes eingesetzt, sondern auch zur Unterstützung von Gewichtsreduktion und zur Verbesserung der Ovulationsrate bei Frauen mit polycystischem Ovarialsyndrom (PCOS).
Zusammenfassend lässt sich sagen, dass Metformin Hydrochlorid ein vielseitiges Medikament ist, das nicht nur die Blutzuckerkontrolle verbessert, sondern auch weitere gesundheitliche Vorteile mit sich bringen kann.
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