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Object.defineProperty(exports, "__esModule", ({ value: true })); exports["default"] = void 0; __webpack_require__(/*! core-js/modules/esnext.iterator.constructor.js */ "../node_modules/core-js/modules/esnext.iterator.constructor.js"); __webpack_require__(/*! core-js/modules/esnext.iterator.find.js */ "../node_modules/core-js/modules/esnext.iterator.find.js"); class Shapes extends elementorModules.frontend.handlers.Base { getDefaultSettings() { return { selectors: { container: '> .elementor-shape-%s' }, svgURL: elementorFrontend.config.urls.assets + 'shapes/' }; } getDefaultElements() { const elements = {}, selectors = this.getSettings('selectors'); elements.$topContainer = this.$element.find(selectors.container.replace('%s', 'top')); elements.$bottomContainer = this.$element.find(selectors.container.replace('%s', 'bottom')); return elements; } isActive() { return elementorFrontend.isEditMode(); } getSvgURL(shapeType, fileName) { let svgURL = this.getSettings('svgURL') + fileName + '.svg'; if (elementor.config.additional_shapes && shapeType in elementor.config.additional_shapes) { svgURL = elementor.config.additional_shapes[shapeType]; if (-1 < fileName.indexOf('-negative')) { svgURL = svgURL.replace('.svg', '-negative.svg'); } } return svgURL; } buildSVG(side) { const baseSettingKey = 'shape_divider_' + side, shapeType = this.getElementSettings(baseSettingKey), $svgContainer = this.elements['$' + side + 'Container']; $svgContainer.attr('data-shape', shapeType); if (!shapeType) { $svgContainer.empty(); // Shape-divider set to 'none' return; } let fileName = shapeType; if (this.getElementSettings(baseSettingKey + '_negative')) { fileName += '-negative'; } const svgURL = this.getSvgURL(shapeType, fileName); jQuery.get(svgURL, data => { $svgContainer.empty().append(data.childNodes[0]); }); this.setNegative(side); } setNegative(side) { this.elements['$' + side + 'Container'].attr('data-negative', !!this.getElementSettings('shape_divider_' + side + '_negative')); } onInit() { if (!this.isActive(this.getSettings())) { return; } super.onInit(...arguments); ['top', 'bottom'].forEach(side => { if (this.getElementSettings('shape_divider_' + side)) { this.buildSVG(side); } }); } onElementChange(propertyName) { const shapeChange = propertyName.match(/^shape_divider_(top|bottom)$/); if (shapeChange) { this.buildSVG(shapeChange[1]); return; } const negativeChange = propertyName.match(/^shape_divider_(top|bottom)_negative$/); if (negativeChange) { this.buildSVG(negativeChange[1]); this.setNegative(negativeChange[1]); } } } exports["default"] = Shapes; /***/ }) }]); //# sourceMappingURL=section-editor-handlers.46a034cbaaa10c6afa92.bundle.js.mapimport Component from './data/component'; import { Templates } from './data/commands'; export default class Module extends elementorModules.editor.utils.Module { onElementorInit() { const config = elementor.documents.getCurrent().config; if ( config.support_site_editor ) { $e.components.register( new Component() ); $e.data.deleteCache( $e.components.get( Component.namespace ), Templates.signature ); } } } @keyframes wobble { from, to { transform: none; } 15% { transform: translate3d(-25%, 0, 0) rotate3d(0, 0, 1, -5deg); } 30% { transform: translate3d(20%, 0, 0) rotate3d(0, 0, 1, 3deg); } 45% { transform: translate3d(-15%, 0, 0) rotate3d(0, 0, 1, -3deg); } 60% { transform: translate3d(10%, 0, 0) rotate3d(0, 0, 1, 2deg); } 75% { transform: translate3d(-5%, 0, 0) rotate3d(0, 0, 1, -1deg); } } .wobble { animation-name: wobble; } 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Aromasin: Eine umfassende Bewertung und Anwendung

Aromasin, der Handelsname für Exemestan, ist ein Medikament, das häufig in der Hormontherapie von Brustkrebs eingesetzt wird. Es gehört zur Kategorie der Aromatasehemmer und wird in der Regel zur Behandlung von postmenopausalen Frauen mit hormonrezeptorpositivem Brustkrebs verwendet. In diesem Artikel betrachten wir die Wirkungsweise, die Anwendungsgebiete sowie die Vor- und Nachteile von Aromasin.

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Wirkungsweise von Aromasin

Aromasin wirkt, indem es die Aromatase-Hormonproduktion hemmt, ein Enzym, das für die Umwandlung von Androgenen in Östrogene verantwortlich ist. Durch die Reduzierung des Östrogenspiegels im Körper wird das Wachstum von hormonabhängigem Brustkrebs verlangsamt oder gestoppt.

Anwendungsgebiete

  1. Postmenopausale Frauen mit hormonrezeptorpositivem Brustkrebs
  2. Prävention von Krebsrückfällen nach der primären Therapie
  3. Therapie bei Metastasen

Vorteile von Aromasin

  • Geringere Nebenwirkungen im Vergleich zu anderen Hormonen
  • Verbesserte Lebensqualität für viele Patientinnen
  • Langfristige Wirksamkeit in der Behandlung von Brustkrebs

Nachteile und Nebenwirkungen

Trotz seiner Vorteile kann die Anwendung von Aromasin auch mit Nebenwirkungen verbunden sein. Dazu gehören:

  • Hitzewallungen
  • Müdigkeit
  • Knochenschmerzen
  • Veränderungen im Cholesterinspiegel

Zusammenfassend ist Aromasin ein wichtiges Medikament in der Behandlung von hormonrezeptorpositivem Brustkrebs bei postmenopausalen Frauen. Es bietet viele Vorteile, doch sollten die potenziellen Nebenwirkungen stets berücksichtigt werden. Patienten sollten vor der Anwendung mit ihrem Arzt über alle Risiken und Nutzen sprechen.